COMPOSITION
Meropenem 500mg Injection
MODE OF ACTION
Meropenem is a broad spectrum Carbapenem antibiotic with bactericidal effects by penetrating bacterial cell readily & interfering with synthesis of cell wall components, which leads to cell death.
Sulbactam is a beta-lactamase inhibitor which blocks the action of enzymes produced by bacteria to inactivate Meropenem. Addition of Sulbactam reduces resistance and enhances the activity of Meropenem against bacteria.
INDICATIONS
- cIAIs
- Sepsis
- Bacterial Meningitis
- SSTI
- HAP
- Acinetobacter infections
- Intra- and post-partum infections
- Clostridium infections
DOSAGE
ADULTS: 500mg-2g depending upon severity & type of infections and dosage should be continued every 8 hours.
PEDIATRICS: 10-40mg/kg depending on the severity & type of infections and dosage should be continued every 8 hours.