COMPOSITION

Linezolid 600mg Tablet

MODE OF ACTION

Linezolid selectively inhibits bacterial protein synthesis through binding to sites on the bacterial ribosome & prevents the formation of a functional 70S-initiation complex.Binds to a site on the bacterial 23S ribosomal RNA of the 50S subunit, prevents the formation of a functional 70S initiation complex, which is an essential component of the bacterial translation process.

INDICATIONS

• Nosocomial Infections
• CAP & VRE Infections
• UTI
• SSTIs

DOSAGE

Community: or hospital-acquired pneumonia: The typical dose is 600mg by mouth every 12 hours for 10 to 14 days.
Complicated skin and soft tissue infections: The typical dose is 600mg by mouth every 12 hours for 10 to 14 days.
Uncomplicated skin and soft tissue infections: For adults, the typical dose is 400mg by mouth every 12 hours for 10 to 14 days. For children 12 years or older, the typical dose is 600mg by mouth every 12 hours for 10 to 14 days.
Vancomycin-resistant Enterococcus faecium (VRE) infection: The typical dose is 600mg by mouth every 12 hours for 14 to 28 days.