ALLITES LIFE SCIENCES

Critical Care

IMISEP

IMISEP 500mg

Imipenem / Cilastatin (Imipenem and Cilastatin for Injection) is a sterile formulation of imipenem (a thienamycin antibiotic) and cilastatin sodium (the inhibitor of the renal dipeptidase, dehydropeptidase l), with sodium bicarbonate added as a buffer. Imipenem / Cilastatin is a potent broad spectrum antibacterial agent for intravenous administration.

THERAPY AREA
: Antibiotic (IV Injectable)
PACKAGING
: 1x1 Vial

COMPOSITION

Imipenem 250mg + Cilastatin 250mg Injection

MODE OF ACTION

Imipenem/Cilastatin is a potent inhibitor of bacterial cell wall synthesis and is bactericidal against a broad spectrum of pathogens gram-positive and gram-negative, aerobic and anaerobic. Absorption Bioavailability (IM): imipenem, 60–75%; cilastatin, 95–100%.

INDICATIONS

Endocarditis
Septicemia
HAP
UTI
VAP
Bone & Joint Infections
Gynecological Infections

DOSAGE

Adult: 1gm IV every 8 hours or 500mg IV every 6 hours
Pediatric: 15mg to 25mg IV/kg/dose every 6 hours