COMPOSITION

Ulinastatin 1,00,000 IU  Injection

MODE OF ACTION

Ulinastatin is a serine protease inhibitor, inhibits several pro-inflammatory proteases and decreases inflammatory cytokine levels and mortality in experimental sepsis. Prevent local inflammation and collateral tissue damage.Ulinastatin, which is a protease inhibitor, prevents trypsinogen to trypsin conversion and further activation of various enzymes and inflammatory response acute pancreatitis.In addition Ulinastatin inhibits the secretion of pro-inflammatory cytokines thus preventing further progression MODS in severe acute pancreatitis.

INDICATIONS

• Acute pancreatitis
• Severe sepsis
• Burns

DOSAGE

Severe Acute Pancreatitis: 2, 00,000 IU BID for 5 Days
Severe Sepsis: 2, 00,000 IU BID for 5 days
Burns & Severe patients: 1,00,000 IU TID for 5-10 days and repeated depending upon severity.